An anonymous reader sends news of a study which found that "two out of five medical students have an unconscious bias against obese people." The study, published in the Journal of Academic Medicine (abstract) examined med students from many different cultural and geographical backgrounds. "The researchers used a computer program called the Weight Implicit Association Test (IAT) to measures students’ unconscious preferences for 'fat' or 'thin' individuals. Students also answered a survey assessing their conscious weight-related preferences. The authors determined if the students were aware of their bias by seeing if their IAT results matched their stated preferences. Overall, 39 percent of medical students had a moderate to strong unconscious anti-fat bias as compared to 17 percent who had a moderate to strong anti-thin bias. Less than 25 percent of students were aware of their biases. 'Because anti-fat stigma is so prevalent and a significant barrier to the treatment of obesity, teaching medical students to recognize and mitigate this bias is crucial to improving the care for the two-thirds of American adults who are now overweight or obese,' Miller said. 'Medical schools should address weight bias as part of a comprehensive obesity curriculum.'"
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New submitter kwyjibo87 writes "The World Health Organization (WHO) publicly expressed dismay yesterday concerning news that intellectual property claims were hindering research on a deadly new emerging virus. Novel coronavirus (nCoV), a member of the same viral genus as the causative agent of SARS, has claimed the lives of 22 people (out of 44 reported infected) and left both researchers and health officials scrambling to develop effective diagnostic tests in addition to possible medications and vaccines against nCoV. Now, however, claims of intellectual property on the new virus are hindering research on nCoV according to the WHO, delaying advancements on tools to prevent further spread of the infection. Stories of intellectual property rights in science hindering advancements in research, particularly in clinical applications, are nothing new; the U.S. Supreme Court recently heard arguments on the validity of patents on the BRCA1/2 genes and has yet to issue a decision. The issue of sharing scientific information in order to promote faster research on emerging pathogens is not limited to intellectual property — a recent article in the journal Nature highlighted a case where Chinese researchers risked having their research scooped after uploading viral sequences to a public database designed aid global scientific collaboration."
MTorrice writes "Medical researchers think specially tailored RNA sequences could kill tumor cells or encourage wound healing by turning off genes in patients' cells. Now researchers have developed a nanocoating for bandages or other medical materials that could deliver these fragile gene-silencing RNAs right where they're needed. The team hopes to produce a bandage that shuts down genes standing in the way of healing in chronic wounds."
AndyKrish writes "A BBC story reports that scientists at Albert Einstein College of Medicine at Yeshiva University found Vitamin C kills drug resistant tuberculosis (abstract). Though results are preliminary — the lead investigator of the study said, 'We have only been able to demonstrate this in a test tube, and we don't know if it will work in humans and in animals' — this is an exciting development in the fight against drug-resistant TB."
New submitter QuantumPion writes "The Environmental Protection Agency released draft guidelines last month that could significantly relax radiation hazard standards in the case of a radiological event in the United States by using risk-based decisions. The goal is to have limits that make sense in an emergency that are different from the limits in day-to-day life. From the article: 'Currently, the only guidance are the extremely strict standards that apply for EPA Superfund sites and nuclear plant decommissioning, which are as low as 0.010–0.025 rem/year, far below the natural background levels in the U.S. of 0.300 rem/year, and even well below the average amount of radioactive materials that Americans eat each year. And these guidelines aren’t really different from the 1992 PAG, except in the area of long-term cleanup standards and, perhaps, standards for resettlement. What’s the big deal here? As radworkers, we’re allowed to get 5 rem/year. 2 rem/year doesn’t rate a second thought. ... No one has ever been harmed by 5 rem/year, so setting emergency levels at 2 rem/year is pretty mild and more than reasonable. ... Think of it this way. The situations covered by these new guidelines are similar to someone dying of thirst who has the chance to drink fresh water having 2,000 pCi per gallon of radium in it. While the safe drinking water levels are 20 pCi/gal for Ra, 2,000 pCi/gal is of no threat, especially if you’re going to die from imminent dehydration. Of course, a bag of potato chips has 3,500 picocuries, so go figure.'"
kkleiner writes "The FDA is finalizing its review of the antibacterial agent triclosan common to many soaps and other health/household products after four decades of use. Recent studies suggest the chemical may be harmful to animals and could interfere with the human immune system along with increasing the proliferation of antibiotic-resistant bacteria. The agency has been slow to cast a verdict, to much criticism considering its widespread use."
sciencehabit writes "If you are one of the 20% of healthy adults who struggle with basic arithmetic, simple tasks like splitting the dinner bill can be excruciating. Now, a new study suggests that a gentle, painless electrical current applied to the brain can boost math performance for up to 6 months. Researchers don't fully understand how it works, however, and there could be side effects." We've covered various other potential benefits to having your brain shocked.
jfruh writes "Larry Page revealed that he'd been suffering from a vocal cord ailment that impaired his ability to speak for more than a year. The positive feedback he got from opening up about it inspired him to tell attendees at Google I/O that we should all be less uptight about keeping our medical records private. As far as Page is concerned, pretty much the only legitimate reason for worry on this score is fear of being denied health insurance. 'Maybe we should change the rules around insurance so that they have to insure people,' he said."
theodp writes "Last summer, unspecified voice problems caused Google CEO Larry Page to miss Google's Annual Shareholder Meeting, the I/O conference, and a quarterly earnings call. Now, Page has come forward and revealed that he suffers from partial paralysis of each of his vocal chords, an 'extremely rare' condition. Not unlike what Sergey Brin and his wife are doing with Parkinson's research, Page and his wife will be funding and overseeing 'a significant research program' led by Dr. Steven Zeitels of Harvard Medical School."
symbolset writes "Research published yesterday in the journal Cell (abstract) by Richard Lee and Amy Wagers of Harvard has isolated GDF-11 as a negative regulator of age-associated cardiac hypertrophy. 'When the protein ... was injected into old mice, which develop thickened heart walls in a manner similar to aging humans, the hearts were reduced in size and thickness, resembling the healthy hearts of younger mice.' Through a type of transfusion called parabiotic or 'shared circulation' in mice — one old and sick, the other young and well — they managed to reverse this age-associated heart disease. From there, they isolated an active agent, GDF-11, present in the younger mouse but absent in the older, which reverses the condition when administered directly. They are also using the agent to restore other aged/diseased tissues and organs. Human applications are expected within six years. Since the basis for the treatment is ordinary sharing of blood between an older ill, and younger healthy patient, we can probably expect someone to start offering the transfusion treatment somewhere in the world, soon, to those with the means to find a young and healthy volunteer."
DavidHumus writes "A recent study indicates that consuming vegetables from the Solanaceae family, which includes tomatoes and peppers (as well as tobacco), decreases the risk of contracting Parkinson's disease. Earlier studies had shown that smoking tobacco seems to provide protection against the disease and the newer one seems to confirm that the key ingredient is nicotine, which is present in some vegetables like peppers."
Arglebarf writes "A family member is recovering from a serious illness and, unfortunately, the medication that saved her life will probably cost her hands and feet. She is an artist by trade, so this is a pretty big deal. Replacement prostheses might restore a degree of independence, as well as enabling her to continue with her creative passions. Do any Slashdotters have experience with replacement hands? What features do you look for? Do any models allow you tweak the software for fine tuning? Beyond the day-to-day uses, she will want something that can hold small objects precisely (e.g. a paintbrush)."
New submitter Big Nemo '60 writes with news that the National Institute of Mental Health is seeking to modernize the diagnosis of mental illness through the use of neuroscience, genetics, etc. From the article: "The world's biggest mental health research institute is abandoning the new version of psychiatry's 'bible' — the Diagnostic and Statistical Manual of Mental Disorders — questioning its validity and stating that 'patients with mental disorders deserve better.' This bombshell comes just weeks before the publication of the fifth revision of the manual, called DSM-5." More importantly, they are going to be shifting funding to research projects that seek to define new categories of mental illness using modern medical science, ignoring the current DSM categorizations: "The strength of each of the editions of DSM has been 'reliability' .. The weakness is its lack of validity. Unlike our definitions of ischemic heart disease, lymphoma, or AIDS, the DSM diagnoses are based on a consensus about clusters of clinical symptoms, not any objective laboratory measure. In the rest of medicine, this would be equivalent to creating diagnostic systems based on the nature of chest pain or the quality of fever. ... NIMH has launched the Research Domain Criteria (RDoC) project to transform diagnosis by incorporating genetics, imaging, cognitive science, and other levels of information to lay the foundation for a new classification system. ... It became immediately clear that we cannot design a system based on biomarkers or cognitive performance because we lack the data. In this sense, RDoC is a framework for collecting the data needed for a new nosology. But it is critical to realize that we cannot succeed if we use DSM categories as the 'gold standard.' ... Imagine deciding that EKGs were not useful because many patients with chest pain did not have EKG changes. That is what we have been doing for decades when we reject a biomarker because it does not detect a DSM category. We need to begin collecting the genetic, imaging, physiologic, and cognitive data to see how all the data — not just the symptoms — cluster and how these clusters relate to treatment response."
Zothecula writes "Instead of traipsing through Florida in search of the Fountain of Youth, Spanish explorer Juan Ponce de León might have been better off turning his search inwards. More specifically, he should have turned his attention to a region of the brain called the hypothalamus. At least that's what research carried out on mice by scientists at New York's Albert Einstein College of Medicine of Yeshiva University suggests. They found that the hypothalamus controls many aspects of aging, opening up the potential to slow down the aging process by altering signal pathways within that part of the brain."
Guppy writes "Does Tylenol reduce existential distress? Acetaminophen (Paracetamol) has been used to relieve mild-to-moderate physical pain for over a century, yet its actual mechanism of action continues to be debated; modern research has demonstrated an intriguing connection with the body's endocannabinoid system, raising the question of whether it may also have subtle psychological effects as well. A recent paper claims Acetaminophen can alter our response to existential challenge; previous findings have suggested that it may blunt the pain of social rejection as well."
Hatta writes "According to researchers from Harvard Medical School, belief in god is correlated with improved outcomes of treatment for depression. Quoting: 'In the study, published in the current issue of Journal of Affective Disorders, researchers comment that people with a moderate to high level of belief in a higher power do significantly better in short-term psychiatric treatment than those without. "Belief was associated with not only improved psychological well-being, but decreases in depression and intention to self-harm," says David H. Rosmarin, Ph.D., an instructor in the Department of Psychiatry at Harvard Medical School.' This raises interesting questions. Does this support the concept of depressive realism? If the association is found to be causal, would it be ethical for a psychiatrist to prescribe religion?"
An anonymous reader writes "Back in the '60s, Bell Labs created a 'paper computer' called CARDIAC so students could learn the fundamentals of computers. Dr. Dobb's recreates the paper computer in an Excel spreadsheet and hints they will show how it gets ported to an FPGA in future installments."
sciencehabit writes "Citing an increasingly bleak outlook for federal research funding, Harvard Medical School is shutting down its major primate center, which has recently experienced the departure of several key scientists and an investigation into its handling of animals. In the announcement, which surprised many primate researchers, the school said it will not seek to renew the New England Primate Research Center's (NEPRC's) 5-year grant from the National Institutes of Health (NIH) and will 'wind down operations' at the center in Southborough, Massachusetts, over the next 2 years. The center, which has a nearly 50-year history, had done groundbreaking work on an AIDS vaccine and developed animal models for diseases such as Parkinson's, among other accomplishments."
kkleiner writes "A new device will keep a liver alive outside of the human body for up to 24 hours. Developed at Oxford, the OrganOx circulates oxygenated red bloods cells and nutrients through the liver while maintaining the proper temperature. Doctors estimate that this new technique could double the number of livers available, saving the lives of thousands who die every year awaiting transplant."
ananyo writes "Two dangerous things together might make a medicine for one of the hardest cancers to treat. In a mouse model of pancreatic cancer, researchers have shown that bacteria can deliver deadly radiation to tumours — exploiting the immune suppression that normally makes the disease so intractable. The researchers coated the bacterium Listeria monocytogenes with radioactive antibodies and injected the bacterium into mice with pancreatic cancer that had spread to multiple sites. After several doses, the mice that had received the radioactive bacteria had 90% fewer metastases compared with mice that had received saline or radiation alone."